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Population genetics. Annual Review of Genetics DOI: A clear review of the relevant questions addressed by empirical population genetics at the time, and the theory that supported it. Nei, Masatoshi. Molecular population genetics and evolution. New York: American Elsevier. A more or less neutralist view of evolutionary genetics, with an effective treatment of the role of population genetics on molecular evolution.

Provine, William B. The origins of theoretical population genetics. Chicago: Univ.

QTL and Association mapping by Bruce Walsh

An easy-to-read account of the people and the concepts behind the often-contentious beginnings of early population genetics theory. Singh, Rama S. Evolutionary genetics: From molecules to morphology.

An Introduction to Population Genetics Theory

Cambridge, UK: Cambridge Univ. One of three large, multichapter volumes edited by Singh and Krimbas as part of a festschrift for Richard Lewontin, this book presents an interesting series of articles from leading figures in the population genetics field. Users without a subscription are not able to see the full content on this page.

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  • An Introduction to Population Genetics Theory - James F. Crow, Motoo Kimura - Google книги.
  • Already a member? This is a relatively short book, and there is clearly a lot of information that could not be included, but the coverage is still thorough. The equation for Watterson's estimator, one classical measure of variability, is derived mathematically, although it is passed by with effectively no explanation.

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    Furthermore, given how much has to be by-passed, it would have been extremely helpful to provide a list of standard symbolic representations and acronyms, alongside the glossary at the end of the book. Unfortunately, there are a few startling points where the treatment seems a bit uneven. In the early chapters, a lot of information comes all in a rush.

    These are very clear explanations, but they just seem out of place given the demands of understanding the rest of this material. In Chapter 8, the material at the start of the chapter is totally dependent on computer simulations, but there is no reference to the software used. The points about the trajectories of new mutations are clearly made, but this was a missed opportunity to teach these analyses in a more interactive way.

    Each chapter concludes with a few selected references though examples or case studies in the text are inconsistently cited. Each chapter has up to 10 follow-up exercises, which are mostly computational but many of them provide a nice mix of calculations and thought experiments. Full solutions to odd-numbered problems are in the book, the rest are available to instructors from the publisher. As for the actual topics, the first two chapters cover more classical population genetics before moving quickly into the coalescent approach. Chapter 1 covers basic vocabulary of genotype frequencies, and Hardy—Weinberg equilibrium, and then Chapter 2 moves on to the Wright—Fisher model for genetic drift.

    After this short introduction to familiar basics, Chapter 3 dives straight into the coalescent. From that point onward the text starts to apply the theoretical foundation to solve increasingly complex problems in different kinds of relevant data. The start is in Chapter 4, which returns to Wright—Fisher models to discuss F -statistics, which describe the variation in allelic frequencies between studied populations, but the authors maintain focus on coalescence here, and use the material in the previous chapter to delve deeper into the issues of drift and migration raised in Chapter 2.

    The following chapters bounce around a little bit, but the focus is on examples that are relevant in an evolutionary context. Chapter 5 includes a long discussion comparing gene trees and species trees, including a well-rounded overview of population methodological approaches, although this naturally is limited to gene trees within species, not among species as in systematics or phylogenetics. The examples in Chapter 5 include global human demography e. The second half of the book, Chapters 7—10, focuses on different aspects of selection, as a sole force or in combination with drift, and how interactions of organisms with each other and their environment drive selection e.

    The final chapter examines the interaction of phenotype and genotype on multiple loci.

    An Introduction to Population Genetics: Theory and Applications

    Overall, the advantage of this book is that it is thorough and covers a good scope of material with links to emerging examples that make the topics very accessible. Although it is presented as an undergraduate textbook, in the present edition it is not a resource that you could pick up and immediately teach from. But the guidelines are there, and the extra input from an instructor to flesh out those fun case studies, anecdotes, and computational aspects would be well rewarded. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.

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    An introduction to population genetics theory - James Franklin Crow, Motoo Kimura - Google книги

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